2025年4月4日，據(jù)歐盟食品安全局（EFSA）消息，應(yīng)歐盟委員會要求，歐盟動物飼料添加劑和產(chǎn)品（FEEDAP）研究小組就谷氨酸棒桿菌CGMCC 7.453發(fā)酵生產(chǎn)的L-賴氨酸硫酸鹽（L-lysine sulfate）作為所有動物飼料添加劑的安全性和有效性發(fā)表科學意見。
經(jīng)過評估，專家小組認為該添加劑對目標物種、消費者和環(huán)境是安全的。評估中的添加劑被認為是所有非反芻動物物種氨基酸L-賴氨酸的有效來源。為了使補充的L-賴氨酸對反芻動物和非反芻動物同樣有效，需要防止其在瘤胃中降解。部分原文報道如下：
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on L-lysine sulfate produced by fermentation with a genetically modified strain of Corynebacterium glutamicum (CGMCC 7.453) when used as a nutritional additive in feed for all animal species. The active substance is L-lysine. The FEEDAP Panel concluded that the production strain qualifies for the qualified presumption of safety (QPS) approach to safety assessment; therefore, L-lysine sulfate produced with C. glutamicum CGMCC 7.453 does not pose any safety concern associated with the production strain. L-Lysine sulfate produced with C. glutamicum CGMCC 7.453 is considered safe for the target species. The FEEDAP Panel has concerns on the use of L-lysine sulfate in water for drinking. When using L-lysine sulfate, the background sulfur/sulfate content in the compound feed should be taken into account. L-Lysine sulfate produced with C. glutamicum CGMCC 7.453 is safe for the consumer and for the environment. based on the information provided in the safety data sheet of the additive under assessment, the FEEDAP Panel concludes that the additive should be considered irritant to skin, eyes and the respiratory tract, and that any exposure to the additive is a risk. L-Lysine sulfate is considered an efficacious source of the essential amino acid L-lysine for non-ruminant animal species. For the supplemental L-lysine to be as efficacious in ruminants as in non-ruminant species, it would require protection against degradation in the rumen.
經(jīng)過評估，專家小組認為該添加劑對目標物種、消費者和環(huán)境是安全的。評估中的添加劑被認為是所有非反芻動物物種氨基酸L-賴氨酸的有效來源。為了使補充的L-賴氨酸對反芻動物和非反芻動物同樣有效，需要防止其在瘤胃中降解。部分原文報道如下：
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on L-lysine sulfate produced by fermentation with a genetically modified strain of Corynebacterium glutamicum (CGMCC 7.453) when used as a nutritional additive in feed for all animal species. The active substance is L-lysine. The FEEDAP Panel concluded that the production strain qualifies for the qualified presumption of safety (QPS) approach to safety assessment; therefore, L-lysine sulfate produced with C. glutamicum CGMCC 7.453 does not pose any safety concern associated with the production strain. L-Lysine sulfate produced with C. glutamicum CGMCC 7.453 is considered safe for the target species. The FEEDAP Panel has concerns on the use of L-lysine sulfate in water for drinking. When using L-lysine sulfate, the background sulfur/sulfate content in the compound feed should be taken into account. L-Lysine sulfate produced with C. glutamicum CGMCC 7.453 is safe for the consumer and for the environment. based on the information provided in the safety data sheet of the additive under assessment, the FEEDAP Panel concludes that the additive should be considered irritant to skin, eyes and the respiratory tract, and that any exposure to the additive is a risk. L-Lysine sulfate is considered an efficacious source of the essential amino acid L-lysine for non-ruminant animal species. For the supplemental L-lysine to be as efficacious in ruminants as in non-ruminant species, it would require protection against degradation in the rumen.
