2025年8月6日，據(jù)歐盟食品安全局（EFSA）消息，應(yīng)歐盟委員會(huì)要求，歐盟動(dòng)物飼料添加劑和產(chǎn)品（FEEDAP）研究小組就大腸桿菌CCTCC M 20231961發(fā)酵生產(chǎn)的L-精氨酸（L-arginine）作為所有動(dòng)物飼料添加劑的安全性和有效性發(fā)表科學(xué)意見。
經(jīng)過評(píng)估，專家小組認(rèn)為該添加劑對(duì)目標(biāo)物種、消費(fèi)者和環(huán)境是安全的。評(píng)估中的添加劑被認(rèn)為是非反芻動(dòng)物物種氨基酸L-精氨酸的有效來源。為了使補(bǔ)充的L-精氨酸對(duì)反芻動(dòng)物和非反芻動(dòng)物同樣有效，需要防止其在瘤胃中降解。部分原文報(bào)道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of L-arginine produced with a genetically modified strain of Escherichia coli (CCTCC M 20231961) as a nutritional feed additive for all animal species and categories. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the production strain E. coli CCTCC M 20231961 does not raise safety concerns. No viable cells or DNA of the production strain are detected in the final product. Therefore, the FEEDAP Panel concludes that the additive does not pose any safety concern regarding the production strain. The use of L-arginine produced by fermentation with E. coli CCTCC M 20231961 in feed is safe for the target species when supplemented in appropriate amounts to the diet according to the nutritional needs of the target species. The FEEDAP Panel has concerns on the use of L-arginine in water for drinking. The use of L-arginine produced by fermentation with E. coli CCTCC M 20231961 in animal nutrition is considered safe for the consumers and for the environment. The FEEDAP Panel cannot conclude on the potential of the additive to be irritant to skin and/or eyes and to be a potential dermal sensitiser. The feed additive consisting of L-arginine produced by fermentation with E. coli CCTCC M 20231961 is regarded as an efficacious source of the amino acid L-arginine for all non-ruminant species. For the supplemental L-arginine to be as efficacious in ruminants as in non-ruminant species, it requires protection against degradation in the rumen.
經(jīng)過評(píng)估，專家小組認(rèn)為該添加劑對(duì)目標(biāo)物種、消費(fèi)者和環(huán)境是安全的。評(píng)估中的添加劑被認(rèn)為是非反芻動(dòng)物物種氨基酸L-精氨酸的有效來源。為了使補(bǔ)充的L-精氨酸對(duì)反芻動(dòng)物和非反芻動(dòng)物同樣有效，需要防止其在瘤胃中降解。部分原文報(bào)道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of L-arginine produced with a genetically modified strain of Escherichia coli (CCTCC M 20231961) as a nutritional feed additive for all animal species and categories. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the production strain E. coli CCTCC M 20231961 does not raise safety concerns. No viable cells or DNA of the production strain are detected in the final product. Therefore, the FEEDAP Panel concludes that the additive does not pose any safety concern regarding the production strain. The use of L-arginine produced by fermentation with E. coli CCTCC M 20231961 in feed is safe for the target species when supplemented in appropriate amounts to the diet according to the nutritional needs of the target species. The FEEDAP Panel has concerns on the use of L-arginine in water for drinking. The use of L-arginine produced by fermentation with E. coli CCTCC M 20231961 in animal nutrition is considered safe for the consumers and for the environment. The FEEDAP Panel cannot conclude on the potential of the additive to be irritant to skin and/or eyes and to be a potential dermal sensitiser. The feed additive consisting of L-arginine produced by fermentation with E. coli CCTCC M 20231961 is regarded as an efficacious source of the amino acid L-arginine for all non-ruminant species. For the supplemental L-arginine to be as efficacious in ruminants as in non-ruminant species, it requires protection against degradation in the rumen.
