2025年6月12日，據(jù)歐盟食品安全局（EFSA）消息，應(yīng)歐盟委員會要求，歐盟動物飼料添加劑和產(chǎn)品（FEEDAP）研究小組就釀酒酵母CBS 146008生產(chǎn)的25-羥膽鈣化醇（25-hydroxycholecalciferol）作為鮭魚、其他魚類和所有其他動物物種(家禽、豬和所有反芻動物除外)飼料添加劑的安全性和有效性發(fā)表科學(xué)意見。
經(jīng)過評估，專家小組認為在建議的使用條件下該添加劑對目標物種、消費者和環(huán)境都是安全的。部分原文報道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 25-hydroxycholecalciferol as a nutritional feed additive for salmonids, other fish species and all other animal species (except poultry, pigs and all ruminants). The additive is currently authorised for use in pigs, poultry and ruminants. The additive is safe for salmonids, other fish species and all other animal species (other than pigs, poultry and ruminants) at the maximum recommended use levels (in mg 25-OH-D3/kg complete feed): 0.8 for salmonids, 0.075 in other fish species and 0.05 for all other animal species (other than poultry, pigs and ruminants). The use of 25-OH-D3 in feed for all animal species under the proposed conditions of use is considered safe for the consumers and the environment. With regard to the safety of users, the additive is not irritant to the skin or eyes. No conclusion on its potential to be a skin sensitiser or on its effects on the respiratory system can be reached due to the absence of data. The FEEDAP Panel concludes that 25-OH-D3, when used as a nutritional additive in feed, is efficacious for all animal species.
經(jīng)過評估，專家小組認為在建議的使用條件下該添加劑對目標物種、消費者和環(huán)境都是安全的。部分原文報道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 25-hydroxycholecalciferol as a nutritional feed additive for salmonids, other fish species and all other animal species (except poultry, pigs and all ruminants). The additive is currently authorised for use in pigs, poultry and ruminants. The additive is safe for salmonids, other fish species and all other animal species (other than pigs, poultry and ruminants) at the maximum recommended use levels (in mg 25-OH-D3/kg complete feed): 0.8 for salmonids, 0.075 in other fish species and 0.05 for all other animal species (other than poultry, pigs and ruminants). The use of 25-OH-D3 in feed for all animal species under the proposed conditions of use is considered safe for the consumers and the environment. With regard to the safety of users, the additive is not irritant to the skin or eyes. No conclusion on its potential to be a skin sensitiser or on its effects on the respiratory system can be reached due to the absence of data. The FEEDAP Panel concludes that 25-OH-D3, when used as a nutritional additive in feed, is efficacious for all animal species.
